Probing biological structure

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We have used size-fractionated, fluorescent dextrans to probe the structure of the cytoplasmic ground substance of living Swiss 3T3 cells by fluorescence recovery after photobleaching and video image processing. The data indicate that the cytoplasm of living cells has a fluid phase viscosity four times greater than water and contains structural barriers that restrict free diffusion of dissolved...

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ژورنال

عنوان ژورنال: Nature

سال: 1989

ISSN: 0028-0836,1476-4687

DOI: 10.1038/339426a0